Motor learning in essential tremor
Identifieur interne : 002207 ( Main/Exploration ); précédent : 002206; suivant : 002208Motor learning in essential tremor
Auteurs : Holly A. Shill [États-Unis] ; Frederick J. De La Vega [États-Unis] ; Johan Samanta [États-Unis] ; Mark Stacy [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-04-30.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Conditionnement.
English descriptors
- KwdEn :
- MESH :
- methods : Electromyography.
- physiology : Blinking, Conditioning, Classical.
- physiopathology : Essential Tremor.
- Adult, Aged, Female, Humans, Male, Middle Aged.
Abstract
Classical conditioning is abnormal in patients with cerebellar degeneration. Pathological studies have recently demonstrated the finding of Purkinje cell loss in a subset of essential tremor (ET). We studied 10 subjects with long duration ET using a blink reflex conditioning paradigm and compared them with nine controls. A 55.6% reduction in motor learning was seen in the first block of stimulation and this finding persisted across all subsequent trials. We conclude that motor learning is significantly abnormal in subjects with advanced ET and likely reflects pathological involvement of the cerebellum. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22479
Affiliations:
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Le document en format XML
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-04-30">2009-04-30</date><biblScope unit="vol">24</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="926">926</biblScope><biblScope unit="page" to="928">928</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">A58FE29758FE3427CC67B99A8F2CC07C474288ED</idno><idno type="DOI">10.1002/mds.22479</idno><idno type="ArticleID">MDS22479</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Blinking (physiology)</term><term>Cerebellum</term><term>Conditioning</term><term>Conditioning, Classical (physiology)</term><term>Electromyography (methods)</term><term>Essential Tremor (physiopathology)</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Motor learning</term><term>Nervous system diseases</term><term>Tremor</term><term>cerebellum</term><term>classical conditioning</term><term>tremor</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Electromyography</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Blinking</term><term>Conditioning, Classical</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Essential Tremor</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Apprentissage moteur</term><term>Cervelet</term><term>Conditionnement</term><term>Pathologie du système nerveux</term><term>Tremblement</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Conditionnement</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="fr">Classical conditioning is abnormal in patients with cerebellar degeneration. Pathological studies have recently demonstrated the finding of Purkinje cell loss in a subset of essential tremor (ET). We studied 10 subjects with long duration ET using a blink reflex conditioning paradigm and compared them with nine controls. A 55.6% reduction in motor learning was seen in the first block of stimulation and this finding persisted across all subsequent trials. We conclude that motor learning is significantly abnormal in subjects with advanced ET and likely reflects pathological involvement of the cerebellum. © 2009 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Arizona</li><li>Californie</li><li>Caroline du Nord</li></region></list><tree><country name="États-Unis"><region name="Arizona"><name sortKey="Shill, Holly A" sort="Shill, Holly A" uniqKey="Shill H" first="Holly A." last="Shill">Holly A. Shill</name></region><name sortKey="De La Vega, Frederick J" sort="De La Vega, Frederick J" uniqKey="De La Vega F" first="Frederick J." last="De La Vega">Frederick J. De La Vega</name><name sortKey="Samanta, Johan" sort="Samanta, Johan" uniqKey="Samanta J" first="Johan" last="Samanta">Johan Samanta</name><name sortKey="Stacy, Mark" sort="Stacy, Mark" uniqKey="Stacy M" first="Mark" last="Stacy">Mark Stacy</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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